Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.69 |
| ▸ | CTSL | P07711 | 1/20 | 0.65 |
| ▸ | CTSS | P25774 | 1/20 | 0.65 |
| ▸ | CTSK | P43235 | 1/20 | 0.65 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TACR1 | P25103 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31465284 | 1.00 | ACE (0.69) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL27902203 | 1.00 | ACE (0.69) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL29419166 | 0.91 | TACR1 (0.65) | ACECTSLCTSSCTSKTACR1 | |
| SCHEMBL30568723 | 0.90 | ACE (0.73) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL16672124 | 0.89 | ALOX15 (0.64) | ACEKDM4EPOLBTP53P2RY14 | |
| SCHEMBL850438 | 0.89 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL29367687 | 0.89 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL1486167 | 0.89 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL30976323 | 0.89 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL1003555 | 0.89 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102807601-B | Aminoacyl-tryptophanyl-5-methoxytryptamine and preparation method and application thereof | UNIV CAPITAL MEDICAL SCIENCES | 2014-02-26 | — | — | CN | disclosed |
| CN-102807601-A | Aminoacyl-tryptophanyl-5-methoxytryptamine and preparation method and application thereof | UNIV CAPITAL MEDICAL | 2012-12-05 | — | — | CN | disclosed |