Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491895 | 0.83 | DAO (0.43) | MTNR1AMTNR1BFLT3PDE3BPDE3A | |
| SCHEMBL27906754 | 0.82 | DAO (0.44) | MTNR1AMTNR1BKMT2ARAB9ANPC1 | |
| SCHEMBL27472079 | 0.81 | SRD5A2 (0.56) | MTNR1AMTNR1BRAB9ANPC1POLB | |
| SCHEMBL28291590 | 0.81 | IDO1 (0.39) | MTNR1AMTNR1BKMT2ARAB9AMEN1 | |
| SCHEMBL28880746 | 0.81 | PTGS2 (0.45) | MTNR1AMTNR1BIDO1 | |
| SCHEMBL27965811 | 0.81 | PARP1 (0.40) | MTNR1AMTNR1BPOLBHRH4 | |
| SCHEMBL27524233 | 0.81 | DAO (0.43) | MTNR1AMTNR1BKMT2ARAB9ANPC1 | |
| SCHEMBL2156821 | 0.80 | MTNR1A (0.64) | MTNR1AMTNR1BKMT2ARAB9AMEN1 | |
| SCHEMBL28168776 | 0.79 | FBP1 (0.48) | MTNR1AMTNR1BKMT2AMEN1POLB | |
| SCHEMBL28291601 | 0.78 | MTNR1A (0.38) | MTNR1AMTNR1BKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-B | Synthetic method of 2-substituted indole derivative | 中国医学科学院药物研究所 | 2021-12-07 | — | — | CN | disclosed |