Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27925053 | 0.98 | RAB9A (0.56) | RAB9ANPC1GAAPOLBPTGS1 | |
| SCHEMBL27907148 | 0.91 | GAA (0.49) | RAB9ANPC1GAAPOLBPTGS1 | |
| SCHEMBL27925087 | 0.85 | NPC1 (0.54) | RAB9ANPC1GAAPTGS2KMT2A | |
| SCHEMBL28804129 | 0.80 | PLTP (0.52) | RAB9ANPC1GAAPTGS2KMT2A | |
| SCHEMBL27925165 | 0.80 | CETP (0.50) | RAB9ANPC1GAAPTGS1PTGS2 | |
| SCHEMBL27907150 | 0.79 | ADORA2A (0.50) | RAB9ANPC1POLBKDM4EKMT2A | |
| SCHEMBL27907145 | 0.78 | PTGDR2 (0.47) | RAB9ANPC1GAAPOLBL3MBTL1 | |
| SCHEMBL28020949 | 0.76 | NPC1 (0.52) | RAB9ANPC1GAAKDM4EKMT2A | |
| SCHEMBL27907146 | 0.74 | CETP (0.58) | GAAPOLBL3MBTL1KDM4EKMT2A | |
| SCHEMBL11368657 | 0.73 | PTGS2 (0.65) | RAB9ANPC1GAAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103159695-B | HIV can be suppressed to copy and to effective thiazole compound of resistance HIV virus strain and its production and use | CAPITAL NORMAL UNIVERSITY (CN) | 2015-08-12 | — | — | CN | claimed |
| CN-103159695-A | Thiazole compound capable of restraining human immunodeficiency virus (HIV) replication and effective against drug-resistant HIV virus strains and preparation method and purpose thereof | UNIV CAPITAL NORMAL | 2013-06-19 | — | — | CN | claimed |
| CN-103159695-B | HIV can be suppressed to copy and to effective thiazole compound of resistance HIV virus strain and its production and use | CAPITAL NORMAL UNIVERSITY (CN) | 2015-08-12 | — | — | CN | disclosed |
| CN-103159695-A | Thiazole compound capable of restraining human immunodeficiency virus (HIV) replication and effective against drug-resistant HIV virus strains and preparation method and purpose thereof | UNIV CAPITAL NORMAL | 2013-06-19 | — | — | CN | disclosed |