Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27925722 | 0.85 | DHODH (0.39) | ALDH1A1L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL27769338 | 0.81 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27769340 | 0.78 | KCNN4 (0.37) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL27748142 | 0.78 | KCNN4 (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL27769319 | 0.76 | ALDH1A1 (0.42) | CNR2CNR1FAAHABHD12RIPK1 | |
| SCHEMBL27769363 | 0.72 | P2RX3 (0.46) | MAPK13 | |
| SCHEMBL4316256 | 0.69 | P2RX3 (0.49) | CNR1DPP4MAPK13 | |
| SCHEMBL27769411 | 0.69 | KCNN4 (0.41) | ALDH1A1L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL27748146 | 0.69 | FABP4 (0.36) | RIPK1ALDH1A1DPP4 | |
| SCHEMBL27748198 | 0.68 | LMNA (0.38) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479250-B | Tetrazole-substituted arylamides | HOFFMANN LA ROCHE | 2013-05-22 | — | — | CN | disclosed |