Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine Acetamide SCHEMBL11215815 | 0.91 | LOXL2 (0.48) | POLBRAB9ANPC1SMN1; SMN2IDO1 | |
| Pyridine Acetamide SCHEMBL29431271 | 0.88 | RAB9A (0.54) | POLBRAB9ANPC1SMN1; SMN2IDO1 | |
| Pyridine Acetamide SCHEMBL176893 | 0.88 | RAB9A (0.54) | POLBRAB9ANPC1SMN1; SMN2IDO1 | |
| Pyridine Acetamide SCHEMBL3723681 | 0.86 | RAB9A (0.53) | POLBRAB9ANPC1SMN1; SMN2IDO1 | |
| Pyridine Acetamide SCHEMBL7432558 | 0.86 | RAB9A (0.53) | POLBRAB9ANPC1SMN1; SMN2IDO1 | |
| Pyridine Acetamide SCHEMBL5709841 | 0.86 | RAB9A (0.53) | POLBRAB9ANPC1SMN1; SMN2IDO1 | |
| SCHEMBL1178369 | 0.82 | CA2 (0.58) | RAB9ACYP19A1SMN1; SMN2ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL2673007 | 0.80 | CA2 (0.56) | RAB9ACYP19A1SMN1; SMN2ALDH1A1GAA | |
| Pyridine Acetamide SCHEMBL10410418 | 0.80 | RAB9A (0.47) | POLBRAB9ANPC1SMN1; SMN2IDO1 | |
| Pyridine SCHEMBL639564 | 0.79 | GAA (0.50) | POLBCYP19A1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10092490-B2 | Method for straightening keratinous fibres using heating means and an amide | L'OREAL (FR) | 2018-10-09 | — | — | US | disclosed |
| US-20100163070-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE | L'OREAL S.A. (FR) | 2010-07-01 | — | — | US | disclosed |
| US-20100028280-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL S.A. (FR) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100028280-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | POLB 349/4885RAB9A 4079/4885NPC1 4391/4885 |
| US-10092490-B2 | Method for straightening keratinous fibres using heating means and an amide | KRT18, TUBB3, KIF5C | POLB 476/4885RAB9A 4578/4885NPC1 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.