Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395278 | 0.81 | ACHE (0.67) | ACHEALDH1A1HTTMEN1CYP3A4 | |
| SCHEMBL10099720 | 0.76 | MEN1 (0.62) | ACHEALDH1A1HTTICMTMEN1 | |
| SCHEMBL5276311 | 0.73 | ACHE (0.78) | ACHE | |
| SCHEMBL2069635 | 0.71 | TP53 (0.59) | ACHEALDH1A1HTTICMTMEN1 | |
| SCHEMBL6629576 | 0.71 | ALDH1A1 (0.52) | ACHEALDH1A1HTTICMTMEN1 | |
| SCHEMBL8329334 | 0.70 | ALDH1A1 (0.50) | ACHEALDH1A1HTTICMTMEN1 | |
| SCHEMBL18457436 | 0.70 | MEN1 (0.55) | ACHEALDH1A1HTTICMTMEN1 | |
| SCHEMBL8041935 | 0.70 | ALDH1A1 (0.50) | ACHEALDH1A1HTTICMTMEN1 | |
| SCHEMBL10460057 | 0.70 | ADRA2C (0.53) | ACHEALDH1A1HTTICMTMEN1 | |
| SCHEMBL27526983 | 0.70 | TP53 (0.53) | ACHEALDH1A1HTTICMTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |