Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25292240 | 0.86 | MGLL (0.56) | TGFBR1ALDH1A1PKMHDAC3HDAC4 | |
| SCHEMBL14834250 | 0.85 | MGLL (0.69) | TGFBR1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL27900248 | 0.84 | TGFBR1 (0.54) | TGFBR1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL27917924 | 0.83 | ALDH1A1 (0.70) | TGFBR1ALDH1A1SMN1; SMN2PKMHDAC3 | |
| SCHEMBL27900131 | 0.83 | FBP1 (0.57) | TGFBR1ALDH1A1SMN1; SMN2HSD11B1PKM | |
| SCHEMBL3129363 | 0.82 | KMT2A (0.51) | GAAHTTCNR1 | |
| SCHEMBL27900249 | 0.80 | TGFBR1 (0.65) | TGFBR1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL27917918 | 0.79 | MGLL (0.51) | TGFBR1ALDH1A1TDP1SMN1; SMN2PKM | |
| SCHEMBL1498303 | 0.79 | CNR1 (0.51) | HTTCA1CA2MMP1MMP2 | |
| SCHEMBL27917838 | 0.78 | BCHE (0.65) | TGFBR1ALDH1A1PKMHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |