Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 9/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917786 | 0.86 | ALDH1A1 (0.62) | TGFBR1ALDH1A1PKMGAAMAPT | |
| SCHEMBL27900248 | 0.86 | TGFBR1 (0.54) | TGFBR1L3MBTL1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL14834064 | 0.83 | MGLL (0.67) | TGFBR1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL27917924 | 0.83 | ALDH1A1 (0.70) | TGFBR1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL27900131 | 0.83 | FBP1 (0.57) | TGFBR1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL27900247 | 0.81 | CNR2 (0.55) | TGFBR1ALDH1A1PKMMAPT | |
| SCHEMBL27917915 | 0.81 | MAPT (0.59) | TGFBR1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27917838 | 0.81 | BCHE (0.65) | TGFBR1ALDH1A1PKM | |
| SCHEMBL27917828 | 0.80 | TGFBR1 (0.59) | TGFBR1L3MBTL1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL27900201 | 0.79 | CCR8 (0.53) | TGFBR1SMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |