Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754152 | 0.90 | LMNA (0.41) | LMNAHPGDMAPTALDH1A1GAA | |
| SCHEMBL19646278 | 0.77 | ALDH1A1 (0.43) | LMNAHPGDMAPTALDH1A1GAA | |
| SCHEMBL752484 | 0.76 | SRD5A2 (0.40) | LMNAHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9199566 | 0.72 | SMN1; SMN2 (0.47) | LMNAHPGDMAPTALDH1A1GAA | |
| SCHEMBL21248208 | 0.71 | SMN1; SMN2 (0.42) | LMNAHPGDMAPTALDH1A1GAA | |
| SCHEMBL756756 | 0.71 | RAB9A (0.48) | LMNAHPGDMAPTALDH1A1GAA | |
| SCHEMBL17848969 | 0.71 | KDM4E (0.47) | HPGDMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL16640636 | 0.70 | TSHR (0.43) | LMNAHPGDMAPTALDH1A1GAA | |
| SCHEMBL753172 | 0.70 | APP (0.38) | LMNAHPGDALDH1A1GAAMAOB | |
| SCHEMBL20101954 | 0.70 | SMN1; SMN2 (0.50) | LMNAHPGDMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181985-A1 | Antiviral Agent | SHIONOGI & CO., LTD. (JP) | 2010-05-05 | — | — | EP | disclosed |