Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16640634 | 0.88 | NOTUM (0.48) | MAPK14ALDH1A1MAPTGAAHPGD | |
| SCHEMBL19646278 | 0.88 | ALDH1A1 (0.43) | TSHRMAPK14KDM4EALDH1A1MAPT | |
| SCHEMBL16415457 | 0.87 | TSHR (0.48) | TSHRKDM4EALDH1A1MAPTGAA | |
| SCHEMBL29220666 | 0.79 | CRHBP (0.43) | TSHRKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL16745602 | 0.79 | MAPT (0.46) | TSHRKDM4EALDH1A1MAPTGAA | |
| SCHEMBL16411434 | 0.76 | NOTUM (0.62) | TSHRALDH1A1MAPTGAAHPGD | |
| SCHEMBL16640630 | 0.75 | KMT2A (0.44) | MAPK14ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL9918732 | 0.75 | ALDH1A1 (0.47) | TSHRKDM4EALDH1A1MAPTGAA | |
| SCHEMBL19646277 | 0.75 | HTT (0.42) | MAPK14ALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL27938749 | 0.74 | SMN1; SMN2 (0.57) | TSHRKDM4EALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9827336-B2 | Radio-pharmaceutical complexes | BAYER AS (NO) | 2017-11-28 | — | — | US | disclosed |
| US-20150147272-A1 | RADIO-PHARMACEUTICAL COMPLEXES | BAYER AS (NO) | 2015-05-28 | — | — | US | disclosed |
| US-20150110817-A1 | RADIO-PHARMACEUTICAL COMPLEXES | BAYER AS (NO) | 2015-04-23 | — | — | US | disclosed |
| US-20150104385-A1 | RADIO-PHARMACEUTICAL COMPLEXES | ALGETA ASA (NO) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150147272-A1 | RADIO-PHARMACEUTICAL COMPLEXES | HCAR3, TYRO3, HCAR1 | TSHR 55/4885MAPK14 4656/4885KDM4E 3537/4885 |
| US-20150104385-A1 | RADIO-PHARMACEUTICAL COMPLEXES | CD22, HAVCR2, CD2 | TSHR 13/4885MAPK14 4708/4885KDM4E 4223/4885 |
| US-20150110817-A1 | RADIO-PHARMACEUTICAL COMPLEXES | TSPO, TK1, HCAR1 | TSHR 64/4885MAPK14 4737/4885KDM4E 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.