SCHEMBL756756

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6093084	0.83	RAB9A (0.49)	RAB9ANPC1KMT2AKDM4ESMN1; SMN2
	SCHEMBL16925455	0.79	LMNA (0.42)	RAB9ANPC1KMT2AKDM4ESMN1; SMN2
	SCHEMBL2791986	0.78	RAB9A (0.46)	RAB9ANPC1KMT2AKDM4ESMN1; SMN2
	SCHEMBL754199	0.77	ALDH1A1 (0.42)	RAB9ANPC1KMT2AKDM4EALDH1A1
	SCHEMBL16921620	0.76	POLB (0.44)	RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1
	SCHEMBL17848969	0.75	KDM4E (0.47)	KMT2AKDM4ESMN1; SMN2ALDH1A1TSHR
	SCHEMBL18803837	0.74	GABRA1 (0.53)	RAB9ANPC1KMT2AKDM4EALDH1A1
	SCHEMBL2354376	0.73	TUBB4A (0.59)	RAB9ANPC1KMT2AKDM4EALDH1A1
	SCHEMBL3416727	0.73	KMT2A (0.46)	KMT2AKDM4EALDH1A1HPGDMAOB
	SCHEMBL1590178	0.72	KMT2A (0.52)	RAB9ANPC1KMT2AKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.