SCHEMBL27923903

SCHEMBL27923903

CCCc1ccccc1[SiH2]OC

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 3/20 0.34
ADRA2A P08913 4/20 0.34
ADRA2B P18089 4/20 0.34
ADRA2C P18825 4/20 0.34
PPARD Q03181 1/20 0.33
AOC3 Q16853 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
NISCH Q9Y2I1 1/20 0.33
HMGCR P04035 1/20 0.32
ALOX5 P09917 1/20 0.32
PTGS2 P35354 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28290082 0.83 GABRA1 (0.38) TAAR1
SCHEMBL6125419 0.82 ADRA2A (0.33) HTR1AADRA2AADRA2BADRA2CPPARD
SCHEMBL28684438 0.79 ADRA2A (0.33) HTR1AADRA2AADRA2BADRA2CPPARG
SCHEMBL29434676 0.79 HTR1A (0.38) HTR1AADRA2AADRA2BADRA2CAOC3
SCHEMBL28675661 0.78 ALDH1A1 (0.30)
SCHEMBL3481942 0.75 HTR1A (0.36) HTR1AADRA2AADRA2BADRA2CAOC3
SCHEMBL1918471 0.75 HTR1A (0.40) HTR1AADRA2AADRA2BADRA2CPPARD
SCHEMBL28667232 0.73
SCHEMBL142479 0.72 ADRA2B (0.44) HTR1AADRA2AADRA2BADRA2CTAAR1
SCHEMBL29488434 0.72 ADRA2B (0.44) HTR1AADRA2AADRA2BADRA2CTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101641767-B Silicon dielectric treating agent for use after etching, process for producing semiconductor device, and semiconductor device FUJITSU LTD 2013-10-30 CN disclosed