SCHEMBL28290082

SCHEMBL28290082

CCc1ccccc1[SiH2]OC

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.38
GABRB2 P47870 4/20 0.38
L3MBTL1 Q9Y468 3/20 0.37
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HPGD P15428 1/20 0.36
ATM Q13315 1/20 0.36
MGLL Q99685 1/20 0.35
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TP53 P04637 2/20 0.32
CYP2D6 P10635 1/20 0.32
IDO1 P14902 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27923903 0.83 HTR1A (0.34) TAAR1
SCHEMBL3766605 0.81 MGLL (0.38) GABRA1GABRB2L3MBTL1MAPTNPSR1
SCHEMBL28291485 0.81 MAPT (0.40) GABRA1GABRB2L3MBTL1MAPTNPSR1
SCHEMBL707826 0.78 MGLL (0.36) GABRA1GABRB2L3MBTL1MAPTNPSR1
SCHEMBL28290049 0.78 GABRA1 (0.34) GABRA1GABRB2L3MBTL1MAPTNPSR1
SCHEMBL706208 0.78 GABRA1 (0.39) GABRA1GABRB2L3MBTL1MAPTNPSR1
SCHEMBL28297295 0.77 CA12 (0.45) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL29434691 0.77 GABRA1 (0.44) GABRA1GABRB2L3MBTL1MAPTNPSR1
SCHEMBL3482388 0.76 L3MBTL1 (0.37) GABRA1GABRB2L3MBTL1MAPTNPSR1
SCHEMBL704566 0.76 GABRA1 (0.38) GABRA1GABRB2L3MBTL1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641482-A The preparation of the cis- -1,4- polydiene of multiple silane functionals with the Si―H addition reaction in situ preparation by polymer glue 株式会社普利司通 2019-04-16 CN disclosed