Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25398414 | 0.81 | NFE2L2 (0.41) | RAD51TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31087411 | 0.81 | NFE2L2 (0.41) | RAD51TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16290051 | 0.74 | ALDH1A1 (0.44) | PDE4ARAD51NOX1SIGMAR1CYP1A1 | |
| SCHEMBL17870933 | 0.74 | TP53 (0.44) | PDE4ARAD51NOX1SIGMAR1CYP1A1 | |
| SCHEMBL29203313 | 0.73 | RAD51 (0.34) | PDE4ARAD51NOX1SIGMAR1CYP1A1 | |
| SCHEMBL16748956 | 0.72 | SIGMAR1 (0.44) | PDE4ARAD51NOX1SIGMAR1CYP1A1 | |
| SCHEMBL13658551 | 0.67 | HTR3E (0.48) | PDE4ANOX1SIGMAR1NPC1CASP3 | |
| SCHEMBL28332034 | 0.67 | L3MBTL1 (0.42) | NOX1SIGMAR1CYP1A2CA1CA2 | |
| SCHEMBL16748957 | 0.67 | PDE4A (0.49) | PDE4ARAD51NOX1SIGMAR1CYP1A1 | |
| SCHEMBL29127008 | 0.66 | HTR3E (0.47) | PDE4ANOX1SIGMAR1NPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103172579-A | Triazole phenyl amines compound preparation and application | TIANJIN INT JOINT ACADEMY BIOTECHNOLOGY & MEDICINE | 2013-06-26 | — | — | CN | disclosed |