Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25398414 | 0.79 | NFE2L2 (0.41) | RAD51 | |
| SCHEMBL16290051 | 0.79 | ALDH1A1 (0.44) | RAD51PDE4ANOX1SIGMAR1CYP1A1 | |
| SCHEMBL17870933 | 0.79 | TP53 (0.44) | RAD51PDE4ANOX1SIGMAR1CYP1A1 | |
| SCHEMBL31087411 | 0.79 | NFE2L2 (0.41) | RAD51 | |
| SCHEMBL16748956 | 0.77 | SIGMAR1 (0.44) | RAD51PDE4ANOX1SIGMAR1CYP1A1 | |
| SCHEMBL28837942 | 0.76 | CA1 (0.42) | RAD51NOX1CA1CA2CA9 | |
| SCHEMBL18834987 | 0.73 | LMNA (0.40) | NOX1 | |
| SCHEMBL27925994 | 0.73 | PDE4A (0.34) | RAD51PDE4ANOX1SIGMAR1CYP1A1 | |
| SCHEMBL28332034 | 0.71 | L3MBTL1 (0.42) | NOX1SIGMAR1CYP1A2CA1CA2 | |
| SCHEMBL16748957 | 0.71 | PDE4A (0.49) | RAD51PDE4ANOX1SIGMAR1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028834-B | Polyaryltriazole and preparation method and application thereof | 东华大学 | 2024-03-12 | — | — | CN | disclosed |
| CN-115093565-B | Polyphenyl sulfone ether triazole and preparation method and application thereof | 东华大学 | 2024-03-12 | — | — | CN | disclosed |