Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | IL1B | P01584 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23927473 | 0.88 | P2RX7 (0.32) | APLNRP2RX7 | |
| SCHEMBL29224201 | 0.82 | SLC6A1 (0.39) | APLNR | |
| SCHEMBL3185201 | 0.82 | SLC6A1 (0.39) | APLNR | |
| SCHEMBL8040596 | 0.77 | APLNR (0.41) | APLNR | |
| SCHEMBL2487994 | 0.76 | BRD4 (0.39) | APLNRP2RX7 | |
| SCHEMBL28158468 | 0.75 | APLNR (0.39) | APLNR | |
| SCHEMBL12206362 | 0.73 | ALDH1A1 (0.38) | APLNR | |
| SCHEMBL1661682 | 0.72 | APLNR (0.36) | APLNR | |
| SCHEMBL16577416 | 0.72 | — | — | |
| SCHEMBL18027852 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492361-A | Substituted 1-benzylcycloalkylcarboxlic acids and use thereof | BAYER IP GMBH | 2014-01-01 | — | — | CN | disclosed |