Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | CASP3 | P42574 | 3/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.47 |
| ▸ | RELA | Q04206 | 3/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27938191 | 0.86 | HSD17B10 (0.54) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27919488 | 0.81 | LMNA (0.53) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9465302 | 0.78 | CHRNA7 (0.47) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9105844 | 0.74 | NPC1 (0.61) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29442076 | 0.74 | NPC1 (0.61) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL903255 | 0.74 | NPC1 (0.61) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28473715 | 0.72 | FAAH (0.60) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5479018 | 0.72 | GABRP (0.51) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6499067 | 0.72 | FAAH (0.49) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| Iodide SCHEMBL8417295 | 0.72 | NPC1 (0.59) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103333131-A | Preparation method of 2-aminobenzoxazole compound | SUZHOU OST ADVANCED MATERIALS CO LTD | 2013-10-02 | — | — | CN | disclosed |