Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27938096 | 0.81 | RAB9A (0.53) | LMNAMAPTMAPK1SMN1; SMN2CASP3 | |
| SCHEMBL9465302 | 0.77 | CHRNA7 (0.47) | LMNACYP1A2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6489959 | 0.74 | PTGES (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30611207 | 0.73 | FAAH (0.55) | NPC1RAB9APTGESPTGS2 | |
| SCHEMBL21153991 | 0.73 | FAAH (0.55) | NPC1RAB9APTGESPTGS2 | |
| SCHEMBL29293567 | 0.73 | KDM4E (0.49) | LMNACYP1A2MAPTTHRBALOX15 | |
| SCHEMBL8349473 | 0.73 | GABRP (0.49) | LMNACYP1A2MAPTTHRBALOX15 | |
| SCHEMBL1672481 | 0.72 | LMNA (0.66) | LMNACYP1A2MAPTTHRBALOX15 | |
| SCHEMBL3101725 | 0.72 | HTR3E (0.55) | PTGESPTGS2 | |
| SCHEMBL6497353 | 0.72 | PTGES (0.54) | PTGESPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103333131-A | Preparation method of 2-aminobenzoxazole compound | SUZHOU OST ADVANCED MATERIALS CO LTD | 2013-10-02 | — | — | CN | disclosed |