Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791614 | 0.81 | LMNA (0.35) | CYP3A4CXCR2ALDH1A1LMNAKMT2A | |
| SCHEMBL20501204 | 0.79 | TSHR (0.47) | POLBALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL28385050 | 0.78 | HSP90AB1 (0.46) | HSP90AB1CYP3A4POLBALDH1A1LMNA | |
| SCHEMBL1260508 | 0.75 | HSP90AB1 (0.47) | HSP90AB1CYP3A4POLBALDH1A1KDM4E | |
| SCHEMBL27537296 | 0.74 | HSP90AB1 (0.42) | HSP90AB1CYP3A4POLBALDH1A1LMNA | |
| SCHEMBL1262272 | 0.71 | PDE4D (0.43) | HSP90AB1CYP3A4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27759983 | 0.70 | ERCC5 (0.51) | POLBCHRNA7ALDH1A1LMNAKDM4E | |
| SCHEMBL2794495 | 0.70 | ALDH1A1 (0.45) | HSP90AB1CYP3A4POLBCHRNA7ALDH1A1 | |
| SCHEMBL24451116 | 0.69 | HSP90AB1 (0.48) | HSP90AB1CYP3A4POLBALDH1A1KDM4E | |
| SCHEMBL9720563 | 0.69 | HSP90AB1 (0.44) | HSP90AB1CYP3A4POLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168087-A1 | BENZO[1,2,3]THIADIAZINE DERIVATES | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2010-07-01 | — | — | US | disclosed |
| EP-2061777-A1 | BENZOÝ1,2,3¨THIADIAZINE DERIVATIVES | Egis Gyogyszergyar Nyilvánosan Múködó Részvénytársaság (HU) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008020255-A1 | BENZO[1,2,3]THIADIAZINE DERIVATIVES | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168087-A1 | BENZO[1,2,3]THIADIAZINE DERIVATES | SULT2A1, TPH1, CYP1A1 | HSP90AB1 377/4885CYP3A4 171/4885CXCR2 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.