Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17224656 | 0.70 | KCNA5 (0.34) | — | |
| SCHEMBL8212485 | 0.69 | KDM5A (0.32) | — | |
| SCHEMBL17881860 | 0.66 | — | — | |
| SCHEMBL4457007 | 0.65 | CES2 (0.50) | CES2CES1BRD4 | |
| SCHEMBL14905655 | 0.65 | CYP4F2 (0.37) | — | |
| SCHEMBL8078157 | 0.61 | CES2 (0.37) | CES2CES1BRD4CREBBP | |
| SCHEMBL4651304 | 0.61 | LMNA (0.48) | CES2CES1 | |
| SCHEMBL29243058 | 0.60 | CES2 (0.38) | CES2CES1 | |
| SCHEMBL34847 | 0.58 | — | — | |
| SCHEMBL2028609 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015641-B | Heterocyclic compound | TAKEDA PHARMACEUTICAL | 2014-01-01 | — | — | CN | disclosed |