SCHEMBL27949280

SCHEMBL27949280

CC(=O)Oc1c[nH]c(C(C)C)n1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.33
MAP3K7 O43318 1/20 0.30
TAB1 Q15750 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4270945 0.76 SLC22A6 (0.36) SLC22A6
SCHEMBL27758389 0.76 LMNA (0.36) SLC22A6
SCHEMBL28455636 0.75 GSK3B (0.44)
SCHEMBL17672382 0.68 HCAR2 (0.43)
SCHEMBL5511367 0.68 ALOX5 (0.43) SLC22A6
SCHEMBL27933983 0.67 GPR84 (0.35)
SCHEMBL21401432 0.67 CNR1 (0.42)
SCHEMBL27894394 0.66 AMY1A (0.40)
SCHEMBL21282680 0.64 CCNE1 (0.42)
SCHEMBL507938 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103492372-B Regulate the Carbox amide of androgen receptor ORION CORP. (FI) 2015-09-30 CN disclosed
CN-103492372-A Androgen receptor modulating carboxamides ORION CORP 2014-01-01 CN disclosed