SCHEMBL4270945

SCHEMBL4270945

CC(=O)Oc1c[nH]c(OC(C)=O)n1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.36
LMNA P02545 2/20 0.32
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30
RAB9A P51151 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8586929 0.80 LMNA (0.36) SLC22A6LMNATSHRNFKB1RAB9A
SCHEMBL27758389 0.80 LMNA (0.36) SLC22A6LMNATSHRNFKB1RAB9A
SCHEMBL27949280 0.76 SLC22A6 (0.33) SLC22A6
SCHEMBL5511367 0.72 ALOX5 (0.43) SLC22A6LMNATSHR
SCHEMBL27933983 0.71 GPR84 (0.35)
SCHEMBL27894394 0.70 AMY1A (0.40) LMNARAB9A
SCHEMBL9547150 0.69 MAP3K7 (0.32)
SCHEMBL507938 0.67
SCHEMBL2518688 0.66 KDM4E (0.46) LMNATSHRACHE
SCHEMBL4265537 0.66 HCAR2 (0.39) LMNATSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed