Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27894394 | 0.84 | AMY1A (0.40) | LMNAALDH1A1TDP1HSD17B10MAPK1 | |
| SCHEMBL10674574 | 0.80 | TSPO (0.50) | MAPTLMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL7517964 | 0.78 | ALDH1A1 (0.42) | MAPTLMNAALDH1A1TDP1HSD17B10 | |
| SCHEMBL811735 | 0.76 | MAPT (0.46) | ADORA3PIN1MAPTALDH1A1TDP1 | |
| SCHEMBL27911625 | 0.76 | PDE5A (0.35) | BACE1SLC22A6MAPTALDH1A1HSD17B10 | |
| Acetone SCHEMBL28130744 | 0.75 | ADORA3 (0.44) | ADORA3PIN1MAPTALDH1A1TDP1 | |
| SCHEMBL17279783 | 0.74 | BACE1 (0.48) | ALOX5ADORA3BACE1MAPTLMNA | |
| SCHEMBL4270945 | 0.72 | SLC22A6 (0.36) | SLC22A6LMNATSHR | |
| SCHEMBL27758389 | 0.72 | LMNA (0.36) | SLC22A6LMNAALDH1A1HSD17B10KDM4E | |
| SCHEMBL27567731 | 0.71 | ADORA3 (0.55) | ADORA3MAPTLMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114946-A2 | ACID-SENSITIVE LINKERS FOR DRUG DELIVERY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-10-11 | — | — | WO | disclosed |