Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030909 | 0.90 | MAPT (0.55) | SMN1; SMN2ANPEPERAP2ERAP1MME | |
| SCHEMBL28030339 | 0.82 | NR1H4 (0.58) | MMECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL28172139 | 0.81 | CYP11B1 (0.52) | SMN1; SMN2CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL27963148 | 0.80 | MAPT (0.39) | SMN1; SMN2MMEMEN1KMT2AMAPT | |
| SCHEMBL28030313 | 0.79 | MME (0.52) | MMECYP1A2MAPTPTPN1 | |
| SCHEMBL7141466 | 0.79 | CYP1A2 (0.67) | CPA1SMN1; SMN2ANPEPERAP2ERAP1 | |
| SCHEMBL28030312 | 0.79 | ALPL (0.51) | MMEMAPTPTPN1 | |
| SCHEMBL10436410 | 0.78 | CPA1 (0.57) | CPA1SMN1; SMN2ANPEPERAP2ERAP1 | |
| SCHEMBL29110788 | 0.76 | MAPT (0.51) | SMN1; SMN2CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL28030907 | 0.72 | NR1H4 (0.58) | MMECYP1A2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787976-B | 1-aryl-3-aryl-1H-pyrazoles-5-first hydroximic acid derivative and application thereof | SHANDONG UNIVERSITY (CN) | 2015-10-28 | — | — | CN | disclosed |