Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142219 | 0.88 | MEN1 (0.39) | GHSRKMT2AMEN1MAPK1APLNR | |
| SCHEMBL76966 | 0.84 | BTK (0.38) | GHSRKMT2AMEN1MAPK1APLNR | |
| SCHEMBL202837 | 0.84 | BTK (0.38) | GHSRKMT2AMEN1MAPK1APLNR | |
| SCHEMBL496169 | 0.83 | FAAH (0.39) | GHSRKMT2AMEN1MAPK1GAA | |
| SCHEMBL8980908 | 0.83 | FAAH (0.39) | GHSRKMT2AMEN1MAPK1GAA | |
| SCHEMBL550992 | 0.83 | FAAH (0.39) | GHSRKMT2AMEN1MAPK1GAA | |
| SCHEMBL8981350 | 0.83 | FAAH (0.39) | GHSRKMT2AMEN1MAPK1GAA | |
| SCHEMBL1012064 | 0.83 | FAAH (0.39) | GHSRKMT2AMEN1MAPK1GAA | |
| SCHEMBL19204868 | 0.83 | GHSR (0.33) | GHSRKMT2AMEN1MAPK1APLNR | |
| SCHEMBL2789711 | 0.82 | GHSR (0.37) | GHSRKMT2AMEN1MAPK1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039796-A | 1-oxo/acylation-14-acylated oridonin derivative, and preparation method and application thereof | HANGZHOU BENSHENG PHARMACEUTICAL CO LTD | 2014-09-10 | — | — | CN | claimed |