Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972621 | 0.88 | NPC1 (0.42) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL28813725 | 0.86 | GRM1 (0.46) | KDM4E | |
| SCHEMBL27972549 | 0.85 | SMO (0.53) | MEN1KMT2ATDP1MAPTRAB9A | |
| SCHEMBL27972279 | 0.83 | FADS1 (0.39) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL28426457 | 0.82 | CHRNB2 (0.43) | MEN1KMT2AALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL27972550 | 0.82 | GRM1 (0.43) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL28261342 | 0.81 | MEN1 (0.52) | MEN1KMT2ATDP1MAPTRAB9A | |
| SCHEMBL28279915 | 0.81 | MEN1 (0.49) | MEN1KMT2ATDP1ALDH1A1ATM | |
| SCHEMBL27972568 | 0.81 | MEN1 (0.53) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL28427586 | 0.81 | JAK2 (0.52) | KMT2AALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104066724-A | P2X4 receptor antagonists | NIPPON CHEMIPHAR CO | 2014-09-24 | — | — | CN | disclosed |