Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.65 |
| ▸ | YAP1 | P46937 | 1/20 | 0.62 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.62 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271694 | 0.86 | RXFP1 (0.70) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL10597386 | 0.81 | LMNA (0.71) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL10601573 | 0.81 | RXFP1 (0.67) | RXFP1YAP1TEAD4TEAD2LMNA | |
| Flufenamic Acid SCHEMBL29356958 | 0.81 | RXFP1 (0.75) | RXFP1YAP1TEAD4TEAD2LMNA | |
| Flufenamic Acid SCHEMBL17497 | 0.81 | RXFP1 (0.75) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL11494752 | 0.81 | LMNA (0.67) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL27980323 | 0.81 | MAPT (0.68) | RXFP1TEAD4ALDH1A1MAPTAKR1C3 | |
| SCHEMBL12715082 | 0.81 | LMNA (0.91) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL12851592 | 0.80 | RXFP1 (0.78) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL9522037 | 0.80 | YAP1 (0.74) | RXFP1YAP1TEAD4TEAD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104098503-A | Isoindoline compound, preparation method and anti-depression application thereof | INST MATERIA MEDICA CAMS | 2014-10-15 | — | — | CN | disclosed |