Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985067 | 0.91 | ACHE (0.52) | CRHR1MAPTTDP1ACHEALDH1A1 | |
| SCHEMBL27985519 | 0.86 | ALDH1A1 (0.49) | MAPTTDP1ACHEALDH1A1MEN1 | |
| SCHEMBL701921 | 0.83 | ACHE (0.47) | MAPTTDP1ACHEALDH1A1MEN1 | |
| SCHEMBL27985066 | 0.82 | MAPT (0.54) | MAPTTDP1ACHEALDH1A1MEN1 | |
| SCHEMBL4959585 | 0.81 | NR3C1 (0.47) | CRHR1MAPTTDP1ALDH1A1KMT2A | |
| SCHEMBL24196241 | 0.81 | L3MBTL1 (0.44) | MAPTTDP1ACHEALDH1A1MEN1 | |
| SCHEMBL27985522 | 0.81 | L3MBTL1 (0.54) | MAPTACHEALDH1A1MEN1KMT2A | |
| SCHEMBL27985068 | 0.81 | ACHE (0.48) | MAPTTDP1ACHEALDH1A1MEN1 | |
| SCHEMBL24196132 | 0.80 | LMNA (0.53) | MAPTTDP1ACHEALDH1A1MEN1 | |
| SCHEMBL8058932 | 0.80 | CRHR1 (0.51) | CRHR1MAPTACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106986865-A | On Mental disease or the compound and medical composition of malignant tumour | 国立大学法人京都大学 | 2017-07-28 | — | — | CN | disclosed |
| CN-104520303-B | Compound and pharmaceutical composition for mental and neurological diseases or malignant tumors | 国立大学法人京都大学 | 2017-04-12 | — | — | CN | disclosed |
| CN-104520303-A | Compound and pharmaceutical composition for mental and neurological diseases or malignant tumors | NAT UNIV CORP KYOTO UNIV | 2015-04-15 | — | — | CN | disclosed |