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SCHEMBL2798958

SCHEMBL2798958

Cc1ccc(S(=O)(=O)O/N=C(\C#N)c2ccsc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.44
▸ TDP1 Q9NUW8 4/20 0.44
▸ ALDH1A1 P00352 6/20 0.42
▸ SMN1; SMN2 Q16637 4/20 0.42
▸ LMNA P02545 3/20 0.42
▸ MEN1 O00255 3/20 0.42
▸ KMT2A Q03164 3/20 0.42
▸ GAA P10253 2/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ C5AR1 P21730 1/20 0.39
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ CA4 P22748 1/20 0.39
▸ CA9 Q16790 1/20 0.39
▸ PKM P14618 3/20 0.35
▸ MAPK1 P28482 3/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ NPSR1 Q6W5P4 2/20 0.35
▸ HSP90AA1 P07900 1/20 0.35
▸ XBP1 P17861 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL382729 1.00 MAPT (0.44) MAPTTDP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL382727 1.00 MAPT (0.44) MAPTTDP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL10083959 0.85 ALDH1A1 (0.40) MAPTTDP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL18957974 0.85 ALDH1A1 (0.40) MAPTTDP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL10097224 0.85 ALDH1A1 (0.40) MAPTTDP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL2262629 0.83 MAPT (0.39) MAPTTDP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL2262634 0.83 MAPT (0.39) MAPTTDP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL1227015 0.82 LMNA (0.42) MAPTTDP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL35981 0.82 LMNA (0.42) MAPTTDP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL35980 0.82 LMNA (0.42) MAPTTDP1ALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1769286-B1 OXIME DERIVATIVES AND THE USE THEROF AS LATENT ACIDS BASF SE (DE) 2015-09-09 — — EP disclosed
US-8241822-B2 Halogenated oxime derivatives and the use therof as latent acids BASF SE (DE) 2012-08-14 — — US disclosed
US-20100167178-A1 Oxime sulfonates and the use thereof as latent acids YAMATO HITOSHI 2010-07-01 — — US disclosed
US-7687220-B2 Oxime derivatives and use thereof as latent acids CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-03-30 — — US disclosed
EP-1320785-B1 OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS BASF SE (DE) 2010-02-17 — — EP disclosed
EP-2030081-A2 OXIME SULFONATES AND THE USE THEROF AS LATENT ACIDS Ciba Holding Inc. (CH) 2009-03-04 — — EP disclosed
US-20080085458-A1 Oxime Derivatives And Use Thereof As Latent Acids CIBA SPECIALTY CHEMICALS CORPORATION 2008-04-10 — — US disclosed
WO-2007147782-A2 OXIME SULFONATES AND THE USE THEROF AS LATENT ACIDS CIBA HOLDING INC. (CH) 2007-12-27 — — WO disclosed
US-7244544-B2 Oxime derivatives and the use thereof as latent acids CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-07-17 — — US disclosed
EP-1769286-A2 OXIME DERIVATIVES AND THE USE THEROF AS LATENT ACIDS Ciba Specialty Chemicals Holding Inc. (CH) 2007-04-04 — — EP disclosed
US-20010037037-A1 Oximesulfonic acid esters and the use thereof as latent sulfonic acids CIBA SPEICIALTY CHEMICALS CORP. 2001-11-01 — — US disclosed
EP-1124832-A1 OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS Ciba SC Holding AG (CH) 2001-08-22 — — EP disclosed
US-6261738-B1 LATENT CURING CATALYSTS FOR PHOTORESISTS SUCH AS 2,2,2-TRIFLUORO-1-PHENYL-ETHANONE OXIME-O-METHYL SULFONATE CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-17 — — US disclosed
EP-1105373-A1 UNSATURATED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS Ciba SC Holding AG (CH) 2001-06-13 — — EP disclosed
WO-2000052530-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-08 — — WO disclosed
WO-2000026219-A1 OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-11 — — WO disclosed
EP-0993445-A1 NEW OXIME SULFONATES AND THE USE THEREOF AS LATENT SULFONIC ACIDS Ciba SC Holding AG (CH) 2000-04-19 — — EP disclosed
WO-2000010972-A1 NEW UNSATURATED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-02 — — WO disclosed
US-6017675-A POLYMERIZATION CATALYST CIBA SPECIALTY CHEMIALS CORPORATION (US) 2000-01-25 — — US disclosed
WO-1999001429-A1 NEW OXIME SULFONATES AND THE USE THEREOF AS LATENT SULFONIC ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-01-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080085458-A1 Oxime Derivatives And Use Thereof As Latent Acids ARSA, CYP2S1, QSOX1 MAPT 4824/4885TDP1 1740/4885ALDH1A1 126/4885
US-20100167178-A1 Oxime sulfonates and the use thereof as latent acids HAO2, SULT2A1, ARSA MAPT 4494/4885TDP1 4134/4885ALDH1A1 62/4885
US-20010037037-A1 Oximesulfonic acid esters and the use thereof as latent sulfonic acids QSOX1, HAO2, PAH MAPT 4475/4885TDP1 1340/4885ALDH1A1 160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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