Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 1/20 | 0.52 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | BPTF | Q12830 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15059636 | 0.83 | SMN1; SMN2 (0.54) | — | |
| SCHEMBL27484183 | 0.74 | FADS1 (0.60) | AURKB | |
| SCHEMBL17538569 | 0.71 | ALDH1A1 (0.63) | AURKB | |
| SCHEMBL27803860 | 0.71 | AURKB (0.57) | AURKBPRKCI | |
| SCHEMBL27929422 | 0.71 | AURKB (0.51) | AURKBPRKCI | |
| SCHEMBL23367948 | 0.70 | SMN1; SMN2 (0.68) | AURKB | |
| SCHEMBL27952999 | 0.70 | AURKB (0.56) | AURKB | |
| SCHEMBL28956237 | 0.70 | KMT2A (0.57) | AURKB | |
| SCHEMBL546885 | 0.70 | AURKB (0.69) | AURKBPRKCI | |
| SCHEMBL27795055 | 0.69 | PLG (0.60) | AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104125947-A | Heterocyclic urea compounds | BIOTA EUROPE LTD | 2014-10-29 | — | — | CN | disclosed |