Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRE | P78334 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28296473 | 0.88 | GABRA5 (0.40) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL11239979 | 0.84 | — | — | |
| SCHEMBL6939540 | 0.84 | ELANE (0.34) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13675135 | 0.79 | — | — | |
| SCHEMBL27530748 | 0.79 | CES2 (0.42) | TSHRPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14763815 | 0.77 | CES2 (0.46) | TSHRPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6881837 | 0.77 | CES2 (0.46) | TSHRPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3997244 | 0.77 | GABRA1 (0.56) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL9205374 | 0.76 | GABRP (0.42) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL27755064 | 0.76 | LMNA (0.40) | GABRA5GABRA1GABRB2TSHRGABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115485279-A | Antibacterial 8-phenylamino-3- (pyrazol-4-yl) imidazo [1,2-a ] pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2022-12-16 | — | — | CN | claimed |
| CN-115485279-A | Antibacterial 8-phenylamino-3- (pyrazol-4-yl) imidazo [1,2-a ] pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-110041335-A | It is a kind of to improve the water-soluble method of couroupitine A, tryptamines ketone derivatives and its preparation method and application | 同济大学 | 2019-07-23 | — | — | CN | disclosed |
| CN-104211635-A | Piperidine compounds, and preparation method, pharmaceutical compositions and use thereof | SHANGHAI INST MATERIA MEDICA | 2014-12-17 | — | — | CN | disclosed |