Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 17/20 | 1.00 |
| ▸ | MMP9 | P14780 | 17/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27992058 | 0.87 | MMP2 (0.78) | MMP2MMP9PTGS1PTGS2L3MBTL1 | |
| SCHEMBL27991879 | 0.80 | MMP2 (1.00) | MMP2MMP9PTGS1PTGS2L3MBTL1 | |
| SCHEMBL27991839 | 0.78 | MMP2 (0.75) | MMP2MMP9PTGS1PTGS2L3MBTL1 | |
| SCHEMBL28810693 | 0.77 | L3MBTL1 (0.79) | MMP2MMP9PTGS2L3MBTL1 | |
| SCHEMBL9356235 | 0.76 | EGFR (1.00) | MMP2MMP9EGFRERBB2 | |
| SCHEMBL28808747 | 0.74 | MMP2 (0.81) | MMP2MMP9PTGS2L3MBTL1 | |
| SCHEMBL27944763 | 0.73 | L3MBTL1 (0.69) | MMP2MMP9L3MBTL1EGFRERBB2 | |
| SCHEMBL14484122 | 0.73 | CA1 (1.00) | MMP2MMP9PTGS2L3MBTL1 | |
| SCHEMBL28020452 | 0.73 | EGFR (0.77) | MMP2MMP9L3MBTL1EGFRERBB2 | |
| SCHEMBL28020561 | 0.72 | APC (0.75) | MMP2MMP9EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230904-A | Synthesis of dihydropyrazol sulfonamide derivatives containing naphthalene ring skeletons and application of dihydropyrazol sulfonamide derivatives in anti-cancer drugs | NANJING UNIVERSITY OF TECHNOLOGY | 2014-12-24 | — | — | CN | disclosed |