Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.79 |
| ▸ | CA2 | P00918 | 11/20 | 0.76 |
| ▸ | CA1 | P00915 | 9/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | GLA | P06280 | 3/20 | 0.76 |
| ▸ | GAA | P10253 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | CFTR | P13569 | 1/20 | 0.76 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.76 |
| ▸ | MMP2 | P08253 | 3/20 | 0.76 |
| ▸ | MMP9 | P14780 | 2/20 | 0.76 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27954385 | 0.91 | CA2 (0.76) | L3MBTL1CA2CA1KDM4EALDH1A1 | |
| SCHEMBL14484122 | 0.86 | CA1 (1.00) | L3MBTL1CA2CA1KDM4EALDH1A1 | |
| SCHEMBL27944763 | 0.86 | L3MBTL1 (0.69) | L3MBTL1CA2CA1KDM4EALDH1A1 | |
| SCHEMBL28808747 | 0.85 | MMP2 (0.81) | L3MBTL1CA2CA1KDM4EALDH1A1 | |
| SCHEMBL27954382 | 0.84 | MMP2 (0.77) | L3MBTL1CA2CA1KDM4EALDH1A1 | |
| SCHEMBL5330451 | 0.82 | MEN1 (1.00) | L3MBTL1CA2CA1KDM4EALDH1A1 | |
| SCHEMBL18826388 | 0.81 | CA1 (0.91) | L3MBTL1CA2CA1KDM4EALDH1A1 | |
| SCHEMBL18826376 | 0.81 | CA1 (0.91) | L3MBTL1CA2CA1KDM4EALDH1A1 | |
| SCHEMBL18826375 | 0.81 | CA1 (0.91) | L3MBTL1CA2CA1KDM4EALDH1A1 | |
| SCHEMBL18826392 | 0.78 | L3MBTL1 (1.00) | L3MBTL1CA2CA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664786-A | Synthesis method of dihydro-pyrazole sulfonamide derivatives of salicylaldehydes and application of dihydro-pyrazole sulfonamide derivatives to preparation of anticancer drugs | NANJING UNIVERSITY OF TECHNOLOGY | 2014-03-26 | — | — | CN | disclosed |