Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | MMP2 | P08253 | 9/20 | 0.65 |
| ▸ | CA12 | O43570 | 3/20 | 0.64 |
| ▸ | CA9 | Q16790 | 3/20 | 0.64 |
| ▸ | MMP9 | P14780 | 8/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810693 | 0.86 | L3MBTL1 (0.79) | L3MBTL1MMP2CA12CA9MMP9 | |
| SCHEMBL27954382 | 0.84 | MMP2 (0.77) | L3MBTL1MMP2CA12CA9MMP9 | |
| SCHEMBL27954385 | 0.84 | CA2 (0.76) | L3MBTL1MMP2CA12CA9MMP9 | |
| SCHEMBL28808747 | 0.81 | MMP2 (0.81) | L3MBTL1MMP2MMP9CA2CA1 | |
| SCHEMBL27997504 | 0.74 | CA1 (0.47) | L3MBTL1MMP2CA12CA9MMP9 | |
| SCHEMBL27955196 | 0.74 | EGFR (0.71) | L3MBTL1MMP2MMP9CA2CA1 | |
| SCHEMBL27992049 | 0.73 | MMP2 (1.00) | L3MBTL1MMP2MMP9EGFRERBB2 | |
| SCHEMBL18826388 | 0.73 | CA1 (0.91) | L3MBTL1MMP2CA12CA9MMP9 | |
| SCHEMBL14484122 | 0.73 | CA1 (1.00) | L3MBTL1MMP2CA12CA9MMP9 | |
| SCHEMBL18826392 | 0.72 | L3MBTL1 (1.00) | L3MBTL1MMP2CA12CA9MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664786-A | Synthesis method of dihydro-pyrazole sulfonamide derivatives of salicylaldehydes and application of dihydro-pyrazole sulfonamide derivatives to preparation of anticancer drugs | NANJING UNIVERSITY OF TECHNOLOGY | 2014-03-26 | — | — | CN | disclosed |