Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28179451 | 0.90 | TDP1 (0.47) | L3MBTL1MAOBALDH1A1REV1MGAM | |
| SCHEMBL28815504 | 0.84 | CYP11B1 (0.51) | BCHEMAOBALDH1A1ABCB1REV1 | |
| SCHEMBL28851823 | 0.84 | CYP11B1 (0.51) | BCHEMAOBALDH1A1ABCB1REV1 | |
| SCHEMBL28178663 | 0.84 | MGAM (0.47) | ALDH1A1ABCB1REV1MEN1KMT2A | |
| SCHEMBL28179447 | 0.84 | REV1 (0.50) | L3MBTL1ALDH1A1ABCB1REV1MEN1 | |
| SCHEMBL28179445 | 0.83 | MAPK14 (0.51) | L3MBTL1BCHEMAOBMAOAALDH1A1 | |
| SCHEMBL27992859 | 0.81 | REV1 (0.53) | L3MBTL1ALDH1A1ABCB1REV1MEN1 | |
| SCHEMBL28179455 | 0.81 | MAOB (0.55) | BCHEMAOBABCB1LMNA | |
| SCHEMBL28179433 | 0.79 | REV1 (0.50) | BCHEMAOBALDH1A1REV1MEN1 | |
| SCHEMBL1666367 | 0.77 | TLR8 (0.48) | L3MBTL1BCHEMAOBKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370793-B | Pyroles marine alkaloids Neolamellarin A analogs and its preparation method and application | 中国海洋大学 | 2017-10-17 | — | — | CN | disclosed |
| CN-104370793-A | Pyrrole ocean alkaloids Neolamellarin A analogue and preparation method and application thereof | OCEAN UNIV CHINA | 2015-02-25 | — | — | CN | disclosed |