Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | LPO | P22079 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28179429 | 0.89 | MAOB (0.53) | MAOBBCHELMNATP53MAPT | |
| SCHEMBL28851823 | 0.89 | CYP11B1 (0.51) | MAOBBCHETP53SIGMAR1ABCB1 | |
| SCHEMBL28815504 | 0.89 | CYP11B1 (0.51) | MAOBBCHETP53SIGMAR1ABCB1 | |
| SCHEMBL28179447 | 0.86 | REV1 (0.50) | LMNAMAPTABCB1 | |
| SCHEMBL28179445 | 0.86 | MAPK14 (0.51) | MAOBBCHELMNATP53MAPT | |
| SCHEMBL28179451 | 0.85 | TDP1 (0.47) | MAOBTP53MAPT | |
| SCHEMBL28178663 | 0.84 | MGAM (0.47) | ABCB1 | |
| SCHEMBL28179465 | 0.82 | CYP11B1 (0.56) | LMNATP53MAPTSIGMAR1 | |
| SCHEMBL27992859 | 0.81 | REV1 (0.53) | LMNATP53MAPTABCB1 | |
| SCHEMBL27992857 | 0.81 | L3MBTL1 (0.51) | MAOBBCHELMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370793-B | Pyroles marine alkaloids Neolamellarin A analogs and its preparation method and application | 中国海洋大学 | 2017-10-17 | — | — | CN | disclosed |
| CN-104370793-A | Pyrrole ocean alkaloids Neolamellarin A analogue and preparation method and application thereof | OCEAN UNIV CHINA | 2015-02-25 | — | — | CN | disclosed |