Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28815504 | 1.00 | CYP11B1 (0.51) | CYP11B1CYP11B2MEN1KMT2ABCHE | |
| SCHEMBL28179445 | 0.92 | MAPK14 (0.51) | MEN1KMT2ABCHECYP19A1NPC1 | |
| SCHEMBL28179465 | 0.91 | CYP11B1 (0.56) | CYP11B1CYP11B2MEN1KMT2ANPC1 | |
| SCHEMBL28179455 | 0.89 | MAOB (0.55) | BCHETP53SIGMAR1FAAHMGLL | |
| SCHEMBL28179429 | 0.88 | MAOB (0.53) | CYP11B1CYP11B2BCHETP53SIGMAR1 | |
| SCHEMBL28179447 | 0.87 | REV1 (0.50) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL27992859 | 0.87 | REV1 (0.53) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL28179433 | 0.84 | REV1 (0.50) | MEN1KMT2ABCHENPC1TP53 | |
| SCHEMBL28178663 | 0.84 | MGAM (0.47) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27992857 | 0.84 | L3MBTL1 (0.51) | MEN1KMT2ABCHEALDH1A1REV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370793-B | Pyroles marine alkaloids Neolamellarin A analogs and its preparation method and application | 中国海洋大学 | 2017-10-17 | — | — | CN | disclosed |