Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27992857 | 0.90 | L3MBTL1 (0.51) | ALDH1A1MAOBGAAREV1MGAM | |
| SCHEMBL28179455 | 0.85 | MAOB (0.55) | MAPTMAOBTP53 | |
| SCHEMBL28851823 | 0.83 | CYP11B1 (0.51) | ALDH1A1KDM4EMAOBSMN1; SMN2REV1 | |
| SCHEMBL28815504 | 0.83 | CYP11B1 (0.51) | ALDH1A1KDM4EMAOBSMN1; SMN2REV1 | |
| SCHEMBL28178663 | 0.83 | MGAM (0.47) | ALDH1A1KDM4EGAASMN1; SMN2REV1 | |
| SCHEMBL28179447 | 0.83 | REV1 (0.50) | ALDH1A1MAPTKDM4EALOX12REV1 | |
| SCHEMBL27992859 | 0.81 | REV1 (0.53) | ALDH1A1MAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL28179445 | 0.80 | MAPK14 (0.51) | ALDH1A1MAPTKDM4EMAOBGAA | |
| SCHEMBL28179429 | 0.80 | MAOB (0.53) | MAPTMAOBREV1TP53CD274 | |
| SCHEMBL28179433 | 0.79 | REV1 (0.50) | ALDH1A1MAPTKDM4EMAOBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370793-B | Pyroles marine alkaloids Neolamellarin A analogs and its preparation method and application | 中国海洋大学 | 2017-10-17 | — | — | CN | disclosed |