Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SI | P14410 | 3/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28178663 | 0.91 | MGAM (0.47) | REV1MGAMGAASIMGAM2 | |
| SCHEMBL28179450 | 0.89 | TUBB4A (0.47) | TP53MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL27992859 | 0.89 | REV1 (0.53) | REV1MGAMGAASIMGAM2 | |
| SCHEMBL28851823 | 0.84 | CYP11B1 (0.51) | REV1MAPK14NPC1TP53MEN1 | |
| SCHEMBL28815504 | 0.84 | CYP11B1 (0.51) | REV1MAPK14NPC1TP53MEN1 | |
| SCHEMBL28179447 | 0.84 | REV1 (0.50) | REV1NPC1MEN1KMT2AKDM4E | |
| SCHEMBL28179429 | 0.83 | MAOB (0.53) | REV1MAPK14TP53MAOBBCHE | |
| SCHEMBL28179445 | 0.81 | MAPK14 (0.51) | GAAMAPK14NPC1TP53MEN1 | |
| SCHEMBL28179455 | 0.79 | MAOB (0.55) | TP53MAOBFAAHMGLLBCHE | |
| SCHEMBL27992857 | 0.79 | L3MBTL1 (0.51) | REV1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370793-B | Pyroles marine alkaloids Neolamellarin A analogs and its preparation method and application | 中国海洋大学 | 2017-10-17 | — | — | CN | disclosed |
| CN-104370793-A | Pyrrole ocean alkaloids Neolamellarin A analogue and preparation method and application thereof | OCEAN UNIV CHINA | 2015-02-25 | — | — | CN | disclosed |