Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27992859 | 0.93 | REV1 (0.53) | REV1CSF1RMAPK1NPC1RAB9A | |
| SCHEMBL28178663 | 0.89 | MGAM (0.47) | REV1ALDH1A1MEN1KMT2AABCB1 | |
| SCHEMBL28815504 | 0.87 | CYP11B1 (0.51) | REV1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL28851823 | 0.87 | CYP11B1 (0.51) | REV1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL28179455 | 0.86 | MAOB (0.55) | MAPTLMNAABCB1 | |
| SCHEMBL28179433 | 0.84 | REV1 (0.50) | REV1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL28179445 | 0.84 | MAPK14 (0.51) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL27992857 | 0.84 | L3MBTL1 (0.51) | REV1ALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL28179451 | 0.83 | TDP1 (0.47) | REV1MAPTALDH1A1ALOX12L3MBTL1 | |
| SCHEMBL28178688 | 0.81 | PDE4A (0.50) | MAPTALDH1A1LMNAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370793-B | Pyroles marine alkaloids Neolamellarin A analogs and its preparation method and application | 中国海洋大学 | 2017-10-17 | — | — | CN | disclosed |