Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 6/20 | 0.37 |
| ▸ | EP300 | Q09472 | 4/20 | 0.37 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417050 | 0.77 | TYMS (0.45) | TYMSMBOAT4PTGER1PTGER4PTGER3 | |
| SCHEMBL27994239 | 0.76 | DHFR (0.66) | TYMS | |
| SCHEMBL27994242 | 0.76 | DHFR (0.66) | TYMS | |
| SCHEMBL7846955 | 0.73 | TYMS (0.66) | TYMS | |
| SCHEMBL8982585 | 0.73 | MBOAT4 (0.54) | TYMSRARBMBOAT4 | |
| SCHEMBL9045691 | 0.72 | TYMS (0.48) | TYMSRARBPTGER1PTGER4PTGER3 | |
| SCHEMBL7836419 | 0.72 | NAMPT (0.56) | TYMSMBOAT4 | |
| SCHEMBL207072 | 0.70 | TYMS (0.49) | TYMSMBOAT4 | |
| SCHEMBL9844768 | 0.66 | TBXAS1 (0.39) | TBXAS1RARBEP300MBOAT4PTGER1 | |
| SCHEMBL2260428 | 0.65 | TYMS (0.69) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104292232-A | Synthesis method for intermediate of impurity A of pemetrexed disodium | SHANDONG BOYUAN PHARMACEUTICAL CO LTD | 2015-01-21 | — | — | CN | disclosed |