Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 6/20 | 0.39 |
| ▸ | EP300 | Q09472 | 6/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27709073 | 0.84 | MBOAT4 (0.50) | TBXAS1EP300MBOAT4ALDH1A1MAPT | |
| SCHEMBL9844833 | 0.82 | DHFR (0.60) | — | |
| SCHEMBL9844798 | 0.81 | PTGER1 (0.42) | TBXAS1RARBEP300PTGER1PTGER4 | |
| SCHEMBL9045691 | 0.74 | TYMS (0.48) | RARBPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL9844766 | 0.72 | KDR (0.46) | EP300MBOAT4 | |
| SCHEMBL9341089 | 0.71 | CYP2D6 (0.53) | TBXAS1RARBMBOAT4MEN1ALDH1A1 | |
| SCHEMBL9844802 | 0.70 | AGTR1 (0.40) | MBOAT4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL9338914 | 0.69 | CYP2D6 (0.56) | RARBEP300MBOAT4MEN1ALDH1A1 | |
| SCHEMBL9343568 | 0.68 | CYP2D6 (0.55) | RARBEP300MBOAT4MEN1ALDH1A1 | |
| SCHEMBL9101705 | 0.68 | CA12 (0.67) | RARBPTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | claimed |
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |