SCHEMBL28001982

SCHEMBL28001982

Cc1cccc(C(=O)c2cccc(O)c2O)c1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.51
CYP3A4 P08684 1/20 0.51
KMT2A Q03164 1/20 0.51
TRPA1 O75762 2/20 0.48
HSD17B10 Q99714 3/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
G6PD P11413 1/20 0.46
CASP7 P55210 1/20 0.46
CASP6 P55212 1/20 0.46
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
SPR P35270 1/20 0.41
ALOX5 P09917 1/20 0.40
TERT O14746 1/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
NPC1 O15118 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2212474 0.87 CD44 (0.50) CYP2C9CYP3A4KMT2AHSD17B10ALDH1A1
SCHEMBL26440502 0.85 CYP3A4 (0.68) CYP2C9CYP3A4KMT2ATRPA1HSD17B10
SCHEMBL28234333 0.82 MMP2 (0.48) CYP2C9CYP3A4KMT2AHSD17B10ALDH1A1
SCHEMBL245254 0.81 FNTA (0.58) CYP2C9CYP3A4KMT2AHSD17B10ALDH1A1
SCHEMBL26441772 0.80 KMT2A (0.56) CYP2C9CYP3A4KMT2ATRPA1HSD17B10
SCHEMBL1758307 0.77 KMT2A (0.78) CYP2C9CYP3A4KMT2ATRPA1HSD17B10
SCHEMBL717462 0.77 G6PD (0.72) CYP3A4HSD17B10ALDH1A1KDM4EHPGD
SCHEMBL18540765 0.77 CYP3A4 (0.71) CYP2C9CYP3A4KMT2ATRPA1HSD17B10
SCHEMBL10768130 0.76 FNTA (0.48) CYP2C9CYP3A4KMT2ATRPA1HSD17B10
SCHEMBL2704894 0.76 ALDH1A1 (0.48) CYP2C9CYP3A4KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104704359-A Methods and compositions for enzyme-mediated site-specific radiolabeling of glycoproteins LIFE TECHNOLOGIES CORP 2015-06-10 CN claimed
CN-110066782-B Recombinant furin substantially free of animal proteins and method for producing same 武田药品工业株式会社 2024-04-16 CN disclosed
CN-109370980-B High-yield transient expression system 生命技术公司 2023-05-09 CN disclosed
CN-110066782-A The substantially recombinant furin and its production method of animal protein-free 百深有限责任公司 2019-07-30 CN disclosed
CN-109476721-A CD 8-specific capture agents, compositions and methods of use and preparation 英蒂分子公司 2019-03-15 CN disclosed
CN-109370980-A High yield transient expression system 生命技术公司 2019-02-22 CN disclosed
CN-104364369-B High yield transient expression in mammalian cells using unique pairs of high density growth and transfection media and expression enhancers 生命技术公司 2018-09-07 CN disclosed
CN-108290927-A I L-17F-specific capture agents, compositions, and methods of use and manufacture 加州理工学院 2018-07-17 CN disclosed
CN-107922961-A Systems and methods for improved transient protein expression in CHO cells 生命技术公司 2018-04-17 CN disclosed
CN-107735110-A NANOPARTICLE IMMUNOCONJUGATES 纪念斯隆-凯特琳癌症中心 2018-02-23 CN disclosed
CN-107624115-A Botulinum neurotoxin specificity capturing agent, composition, application method and manufacture method 加州理工学院 2018-01-23 CN disclosed
CN-104704359-A Methods and compositions for enzyme-mediated site-specific radiolabeling of glycoproteins LIFE TECHNOLOGIES CORP 2015-06-10 CN disclosed
CN-104364369-A High yield transient expression in mammalian cells using unique pairs of high density growth and transfection media and expression enhancers LIFE TECHNOLOGIES CORP 2015-02-18 CN disclosed