Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796657 | 1.00 | EDNRB (0.43) | EDNRBEDNRAALDH1A1SMN1; SMN2GLS | |
| SCHEMBL8566794 | 0.84 | GLS (0.39) | EDNRBEDNRAGLSPOLBGAA | |
| SCHEMBL11602670 | 0.84 | SIRT1 (0.41) | EDNRBEDNRAALDH1A1SMN1; SMN2GLS | |
| SCHEMBL916737 | 0.81 | ALDH1A1 (0.53) | EDNRBEDNRAALDH1A1SMN1; SMN2GLS | |
| SCHEMBL28850201 | 0.81 | ALDH1A1 (0.53) | EDNRBEDNRAALDH1A1SMN1; SMN2GLS | |
| SCHEMBL14374999 | 0.80 | GLS (0.39) | GLSPIN1P2RX7LMNA | |
| SCHEMBL8487887 | 0.80 | GLS (0.39) | EDNRBEDNRAALDH1A1GLSHSD17B10 | |
| SCHEMBL6392161 | 0.80 | PIN1 (0.40) | ALDH1A1GLSPOLBGAAPIN1 | |
| SCHEMBL8370418 | 0.76 | ALDH1A1 (0.48) | EDNRBEDNRAALDH1A1RAB9A | |
| SCHEMBL2790690 | 0.76 | PIN1 (0.60) | PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104583177-B | Aryl alkyl amines as calcium-sensing receptor regulator | 卢平亚特兰蒂斯控股有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-104583177-A | Arylalkylamine compounds as calcium sensing receptor modulators | LUPIN LTD | 2015-04-29 | — | — | CN | disclosed |