Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20746327 | 0.80 | CHRNB2 (0.43) | LMNACYP1A2CYP2D6TP53ALDH1A1 | |
| SCHEMBL3290862 | 0.69 | GFER (0.60) | LMNACYP2D6ALDH1A1RAB9ASMN1; SMN2 | |
| Bromide SCHEMBL6206034 | 0.68 | TP53 (0.53) | CYP1A2CYP2D6TP53ALDH1A1RAB9A | |
| SCHEMBL1147751 | 0.68 | LMNA (0.53) | TAAR1LMNAPOLBTP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4211382 | 0.67 | ALDH1A1 (0.56) | TAAR1LMNAPOLBTSHRTP53 | |
| SCHEMBL17831415 | 0.66 | EPHX1 (0.42) | TAAR1LMNACYP1A2CYP2D6POLB | |
| SCHEMBL2017733 | 0.66 | ALDH1A1 (0.82) | TAAR1LMNAPOLBTSHRTP53 | |
| SCHEMBL8726368 | 0.65 | CALM1 (0.39) | TAAR1LMNACYP1A2CYP2D6POLB | |
| SCHEMBL697719 | 0.65 | TAAR1 (0.44) | TAAR1LMNACYP1A2CYP2D6POLB | |
| SCHEMBL2665231 | 0.64 | CALM1 (0.38) | TAAR1LMNACYP1A2CYP2D6ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106032365-B | Benzal thiazolinone of 2 (base of thiazole 2) imino group 5 and preparation method and application | 湖南大学 | 2018-03-23 | — | — | CN | disclosed |
| CN-105985298-A | 2-[5-(halogenothiazolyl-2-yl)imino]-5-benzalthiazolinone and its preparation method and use | 湖南大学 | 2016-10-05 | — | — | CN | disclosed |
| CN-103304507-B | Green method for preparing heterocyclic compounds from nitriles | UNIV WENZHOU | 2015-02-25 | — | — | CN | disclosed |