Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939775 | 0.83 | CALM1 (0.43) | PTPN5 | |
| SCHEMBL9900323 | 0.77 | — | — | |
| SCHEMBL101479 | 0.74 | PDK2 (0.31) | — | |
| SCHEMBL15286936 | 0.74 | ALOX5 (0.38) | PTPN5MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL6235988 | 0.73 | TRPA1 (0.33) | HTR2AHTR2B | |
| SCHEMBL11926053 | 0.70 | P2RX3 (0.50) | PTPN5P2RX3ALDH1A1IDO1TAAR1 | |
| SCHEMBL21630312 | 0.70 | AR (0.51) | MEN1MAPTKMT2AALDH1A1AR | |
| SCHEMBL542609 | 0.69 | IDO1 (0.44) | MEN1MAPTKMT2AALDH1A1HSP90AB1 | |
| SCHEMBL1106684 | 0.68 | IDO1 (0.58) | MEN1MAPTKMT2AALDH1A1HSP90AB1 | |
| SCHEMBL8754943 | 0.66 | MEN1 (0.38) | MEN1MAPTKMT2AALDH1A1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596923-B | 1,2, 4-thiazolidin-3-one derivatives and their use in the treatment of cancer | BALTIC BIO AB | 2015-04-29 | — | — | CN | claimed |
| CN-102596923-B | 1,2, 4-thiazolidin-3-one derivatives and their use in the treatment of cancer | BALTIC BIO AB | 2015-04-29 | — | — | CN | disclosed |