Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176609 | 0.87 | ALDH1A1 (0.45) | LMNAKMT2AALDH1A1LTA4H | |
| SCHEMBL3036816 | 0.85 | TAAR1 (0.52) | IDO1TAAR1LMNACYP2A6AGXT | |
| SCHEMBL27182261 | 0.84 | CALM1 (0.52) | LMNAMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL320687 | 0.84 | CALM1 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL1106684 | 0.84 | IDO1 (0.58) | IDO1TAAR1LMNACYP2A6MEN1 | |
| SCHEMBL4574058 | 0.79 | CHRM2 (0.53) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8524725 | 0.78 | SLC6A2 (0.49) | IDO1TAAR1LMNASLC6A4ALDH1A1 | |
| SCHEMBL3032392 | 0.76 | SLC6A2 (0.53) | IDO1TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8900207 | 0.76 | SIGMAR1 (0.37) | IDO1TAAR1LMNAMEN1MAPT | |
| SCHEMBL3022914 | 0.76 | PNMT (0.50) | IDO1TAAR1AGXTDAOLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382884-A | Synthesis method of beta-iodo-N-alkoxy benzotriazole compound | 浙江工业大学 | 2017-11-24 | — | — | CN | claimed |
| CN-107382821-A | Synthesis method of beta-iodine-N-alkoxy amine compound | 浙江工业大学 | 2017-11-24 | — | — | CN | claimed |
| CN-106187858-A | A kind of synthetic method of β iodine N alkoxyamine compounds | 浙江工业大学 | 2016-12-07 | — | — | CN | claimed |
| CN-107382884-B | Synthesis method of beta-iodo-N-alkoxy benzotriazole compound | 浙江工业大学 | 2020-10-09 | — | — | CN | disclosed |
| CN-111377923-A | Pyrido [3',2':6, 7] azepino [4,3,2-cd ] isoindolone derivatives and application thereof | 中国药科大学 | 2020-07-07 | — | — | CN | disclosed |
| CN-107382821-B | Synthesis method of β -iodine-N-alkoxy amine compound | 浙江工业大学 | 2020-02-21 | — | — | CN | disclosed |
| CN-107382884-A | Synthesis method of beta-iodo-N-alkoxy benzotriazole compound | 浙江工业大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-107382821-A | Synthesis method of beta-iodine-N-alkoxy amine compound | 浙江工业大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-107382887-A | Method for synthesizing N-alkenyloxy benzotriazoles compound | 浙江工业大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-106187858-A | A kind of synthetic method of β iodine N alkoxyamine compounds | 浙江工业大学 | 2016-12-07 | — | — | CN | disclosed |
| US-20130261130-A1 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2013-10-03 | — | — | US | disclosed |
| EP-0524419-A1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-4483999-A | Phenoxy alkanoic acid derivatives having the ability to lower the level of fatty substances in the blood | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1984-11-20 | — | — | US | disclosed |
| EP-0007347-B1 | ALKYLENGLYCOL COMPOUNDS FOR LOWERING THE LIPID CONTENT AND PROCESSES FOR THE PREPARATION THEREOF | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1981-12-30 | — | — | EP | disclosed |
| US-4275068-A | (BENZYLPHENOXY)-ALKANOLS AS ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | SIEGFRIED AG (CH) | 1981-06-23 | — | — | US | disclosed |
| EP-0007347-A1 | Alkylenglycol compounds for lowering the lipid content and processes for the preparation thereof. | SIEGFRIED AG (CH) | 1980-02-06 | — | — | EP | disclosed |
| US-4182902-A | P-(P'-CHLOROBENZYL) PHENOXYACETIC ACID | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-01-08 | — | — | US | disclosed |
| US-4153803-A | Cholesterol-lowering phenoxyalkanoic acid esters | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1979-05-08 | — | — | US | disclosed |
| WO-1979000116-A1 | NEW GLYCOL COMPOUNDS FOR LOWERING THE LIPID CONTENT | SIEGFRIED AG (CH) | 1979-03-08 | — | — | WO | disclosed |
| US-4115393-A | Pyridyl alkyl esters of substituted phenoxy alkanoic acids having the ability to reduce the level of fatty substances in the blood | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261130-A1 | NEUROTRYPSIN INHIBITORS | MTPN, CHRNA7, CHRNA10 | IDO1 4088/4885TAAR1 878/4885LMNA 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.