SCHEMBL28009494

SCHEMBL28009494

CCOC(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.53
MME P08473 5/20 0.47
ATM Q13315 1/20 0.42
ITGB3 P05106 1/20 0.38
ITGAV P06756 1/20 0.38
GAA P10253 2/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
MAPK1 P28482 1/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
CA2 P00918 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
CAD P27708 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28710585 1.00 TGFBR1 (0.53) TGFBR1MMEATMITGB3ITGAV
SCHEMBL17224588 1.00 TGFBR1 (0.53) TGFBR1MMEATMITGB3ITGAV
Hydrochloric Acid SCHEMBL27571440 0.98 TGFBR1 (0.52) TGFBR1MMEATMITGB3ITGAV
Water SCHEMBL27606033 0.98 TGFBR1 (0.52) TGFBR1MMEATMITGB3ITGAV
SCHEMBL9830204 0.86 ATM (0.40) TGFBR1MMEATMITGB3ITGAV
SCHEMBL12354490 0.85 TGFBR1 (0.50) TGFBR1MMECA2CA12CA1
SCHEMBL2355614 0.82 SMN1; SMN2 (0.57) TGFBR1ATMITGB3ITGAVGAA
SCHEMBL11410899 0.82 ATM (0.38) TGFBR1ATMITGB3ITGAVGAA
SCHEMBL8142588 0.82 CAD (0.39) TGFBR1ATMITGB3ITGAVGAA
SCHEMBL2355611 0.82 SMN1; SMN2 (0.57) TGFBR1ATMITGB3ITGAVGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325680-A1 HIGH-PERMEABILITY PROTEIN OR POLYPEPTIDE CONJUGATE AND USE THEREOF Hangzhou Tito Biotechnology Partnership Enterprise ( Limited Partnership ) (CN) 2025-10-23 US disclosed
US-20250319192-A1 EFFICIENT TRANSDERMAL DELIVERY SYSTEM FOR ACIDIC GROUP-CONTAINING BIOMATERIAL Hangzhou Tito Biotechnology Partnership Enterprise (Limited Partnership) (CN) 2025-10-16 US disclosed
EP-4623901-A1 EFFICIENT TRANSDERMAL DELIVERY SYSTEM FOR ACIDIC GROUP-CONTAINING BIOMATERIAL Hangzhou Tito Biotechnology Partnership Enterprise (Limited Partnership) (CN) 2025-10-01 EP disclosed
EP-4623933-A1 HIGH-PERMEABILITY PROTEIN OR POLYPEPTIDE CONJUGATE, AND USE THEREOF Hangzhou Tito Biotechnology Partnership Enterprise (Limited Partnership) (CN) 2025-10-01 EP disclosed
WO-2024159948-A1 HIGH-PERMEABILITY PROTEIN OR POLYPEPTIDE CONJUGATE, AND USE THEREOF 浙江大学 2024-08-08 WO disclosed
WO-2024152821-A1 EFFICIENT TRANSDERMAL DELIVERY SYSTEM FOR ACIDIC GROUP-CONTAINING BIOMATERIAL 浙江大学 2024-07-25 WO disclosed
CN-101970394-B Novel cyclic hydrocarbon compounds for the treatment of diseases LEO PHARMA AS 2015-05-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325680-A1 HIGH-PERMEABILITY PROTEIN OR POLYPEPTIDE CONJUGATE AND USE THEREOF IAPP, IGFBP1, INSRR TGFBR1 2179/4885MME 1747/4885ATM 3373/4885
US-20250319192-A1 EFFICIENT TRANSDERMAL DELIVERY SYSTEM FOR ACIDIC GROUP-CONTAINING BIOMATERIAL PLAT, MMP1, MMP13 TGFBR1 932/4885MME 1330/4885ATM 1893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.