SCHEMBL2801217

SCHEMBL2801217

NCC(N)CNC1CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.54
ANPEP P15144 2/20 0.52
ERAP2 Q6P179 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.43
EPHX1 P07099 1/20 0.43
HTT P42858 1/20 0.43
TP53 P04637 1/20 0.40
LMNA P02545 2/20 0.39
GMNN O75496 1/20 0.39
MAPT P10636 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
DPP7 Q9UHL4 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
SCN1A P35498 1/20 0.34
SCN2A Q99250 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29100048 0.98 KDM4E (0.50) KDM4EANPEPERAP2SMN1; SMN2EPHX1
SCHEMBL9810147 0.83 KDM4E (0.50) KDM4EANPEPERAP2SMN1; SMN2EPHX1
SCHEMBL3585774 0.83 KDM4E (0.50) KDM4EANPEPERAP2SMN1; SMN2EPHX1
SCHEMBL28080703 0.81 KDM4E (0.52) KDM4EANPEPERAP2SMN1; SMN2EPHX1
SCHEMBL11437981 0.78 KDM4E (0.48) KDM4EANPEPERAP2SMN1; SMN2EPHX1
SCHEMBL28834995 0.77 KDM4E (0.52) KDM4EANPEPERAP2SMN1; SMN2EPHX1
SCHEMBL18263370 0.77 KDM4E (0.57) KDM4EANPEPERAP2SMN1; SMN2EPHX1
SCHEMBL9516706 0.77 KDM4E (0.76) KDM4EANPEPERAP2SMN1; SMN2EPHX1
SCHEMBL3154036 0.76 KDM4E (0.68) KDM4EANPEPERAP2SMN1; SMN2HTT
SCHEMBL1443685 0.76 KDM4E (0.56) KDM4EANPEPERAP2SMN1; SMN2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1983029-B1 Casing made from a polyamide moulding material with improved flowing capability, its production and application EMS PATENT AG (CH) 2017-03-15 EP disclosed
EP-1882018-B1 POLYAMIDE MOLDING MATERIALS WITH AN IMPROVED FLOWABILITY, THE PRODUCTION THEREOF AND ITS USE EMS-CHEMIE AG (CH) 2017-03-08 EP disclosed
US-7786222-B2 Polyamide oligomers and their use EMS-CHEMIE AG (CH) 2010-08-31 US disclosed
US-20090131674-A1 POLYMIDE OLIGOMERS AND THEIR USE EMS-CHEMIE AG (CH) 2009-05-21 US disclosed
EP-1983029-A2 Casing made from a polyamide moulding material with improved flowing capability, its production and application EMS-PATENT AG (CH) 2008-10-22 EP disclosed
EP-1882018-A1 POLYAMIDE MOLDING MATERIALS WITH AN IMPROVED FLOWABILITY, THE PRODUCTION THEREOF AND ITS USE EMS-CHEMIE AG (CH) 2008-01-30 EP disclosed
WO-2006122602-A1 POLYAMIDE MOLDING MATERIALS WITH AN IMPROVED FLOWABILITY, THE PRODUCTION THEREOF AND ITS USE EMS-CHEMIE AG (CH) 2006-11-23 WO disclosed
WO-2006122633-A1 POLYAMIDE OLIGOMERS AND THEIR USE EMS-CHEMIE AG (CH) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131674-A1 POLYMIDE OLIGOMERS AND THEIR USE PUF60, PARG, PARN KDM4E 2988/4885ANPEP 988/4885ERAP2 3076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.