Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800461 | 0.82 | CHRM3 (0.37) | ALDH1A1OPRM1OPRL1CHRM3CHRM2 | |
| SCHEMBL4713396 | 0.81 | ALDH1A1 (0.35) | ALDH1A1OPRM1OPRL1SOAT1EPHX2 | |
| SCHEMBL2800622 | 0.79 | LMNA (0.43) | ALDH1A1OPRM1L3MBTL1 | |
| SCHEMBL19032591 | 0.76 | EPHX2 (0.40) | SOAT1EPHX2L3MBTL1HRH4HRH3 | |
| SCHEMBL19839361 | 0.76 | TACR1 (0.37) | OPRM1OPRL1EPHX2DPP4SLC6A4 | |
| SCHEMBL22034844 | 0.76 | ALDH1A1 (0.44) | ALDH1A1OPRM1CHRM3CHRM2CHRM1 | |
| SCHEMBL26649008 | 0.76 | ALDH1A1 (0.44) | ALDH1A1OPRM1CHRM3CHRM2CHRM1 | |
| SCHEMBL31057226 | 0.74 | LTA4H (0.51) | ALDH1A1SIGMAR1HRH3 | |
| SCHEMBL19032799 | 0.74 | EPHX2 (0.35) | OPRM1OPRL1SOAT1EPHX2L3MBTL1 | |
| SCHEMBL19032868 | 0.74 | EPHX2 (0.35) | OPRM1OPRL1SOAT1EPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100166819-A1 | Transforming Growth Factor Modulators | BIOGEN IDEC MA INC. A CORPORATION | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100166819-A1 | Transforming Growth Factor Modulators | ACVR1, TGFBR1, ACVRL1 | ALDH1A1 656/4885OPRM1 1875/4885OPRL1 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.